Analysis of the relationship of age and topographic distribution of lipofuscin concentration in the retinal pigment epithelium.

Description

by Hiu-ming Li. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1993. / Includes bibliographical references (leaves 81-88). / SUMMARY --- p.1 / Chapter CHAPTER 1. --- INTRODUCTION --- p.3 / Chapter CHAPTER 2. --- LITERATURE REVIEW --- p.7 / Chapter 2.1. --- Retinal pigment epithelium --- p.7 / Chapter 2.1.1. --- Embryology / Chapter 2.1.2. --- Anatomy and histology / Chapter 2.1.3. --- Growth and aging / Chapter 2.1.4. --- Macular region / Chapter 2.2. --- The photoreceptor outer segment --- p.12 / Chapter 2.3. --- Lipofuscin --- p.13 / Chapter 2.4. --- Lipofuscin in retinal pigment epithelium and retinal photoreceptor disc shedding --- p.14 / Chapter 2.5. --- Possible mechanism for lipofuscin formation in the RPE --- p.22 / Chapter 2.6. --- Age-related lipofuscin accumulation in the RPE --- p.22 / Chapter 2.7. --- Racial difference of RPE lipofuscin concentration --- p.25 / Chapter 2.8. --- RPE lipofuscin and age-related macular degeneration --- p.26 / Chapter CHAPTER 3. --- MATERIALS AND METHODS --- p.28 / Chapter 3.1. --- Histologic Specimens --- p.28 / Chapter 3.2. --- Measuring equipment --- p.28 / Chapter 3.3. --- Software of measurements --- p.31 / Chapter 3.4. --- Light source and filters --- p.31 / Chapter 3.5. --- Control --- p.31 / Chapter 3.6. --- Measurement of autofluorescent Intensity --- p.32 / Chapter 3.7. --- Bleaching (oxidation) of melanin --- p.39 / Chapter CHAPTER 4. --- RESULTS --- p.42 / Chapter 4.1. --- Bleaching test --- p.42 / Chapter 4.2. --- RPE autofluorescence observation in different age --- p.43 / Chapter 4.3. --- RPE autofluorescence observation within individual eyes --- p.45 / Chapter 4.4. --- Topographic distribution of lipofuscin --- p.49 / Chapter 4.5. --- Lipofuscin content at the Foveola --- p.50 / Chapter 4.6. --- The relationship of age and lipofuscin content in total RPE --- p.51 / Chapter 4.7. --- The relationship of age and lipofuscin content in the macular RPE --- p.57 / Chapter 4.8. --- Relationship of age and lipofuscin content in the posterior pole of RPE --- p.59 / Chapter 4.9. --- Relationship of age and lipofuscin content in the temporal RPE --- p.61 / Chapter 4.10. --- Relationship of age and lipofuscin content in the nasal RPE --- p.63 / Chapter 4.11. --- Age related topographic changes --- p.65 / Chapter 4.12. --- The relationship of age and lipofuscin content in the RPE of male --- p.66 / Chapter 4.13. --- The relationship of age and lipofuscin content in the RPE of female --- p.68 / Chapter 4.14. --- Relationship of lipofuscin content in different sex --- p.70 / Chapter CHAPTER 5. --- DISCUSSION --- p.71 / Chapter 5.1. --- Evaluation of method --- p.71 / Chapter 5.2. --- RPE lipofuscin content in different age --- p.71 / Chapter 5.3. --- Topographic distribution of lipofuscin --- p.74 / Chapter 5.4. --- Lipofuscin and age-related macular degeneration in Chinese --- p.78 / REFERENCES --- p.81

Links & Downloads

1. cuhk:319254
2. http://library.cuhk.edu.hk/record=b5887706
3. http://repository.lib.cuhk.edu.hk/en/item/cuhk-319254

Tags

Pigment Epithelium of Eye

Lipofuscin

Age Factors

Additional Fields

Identifer	oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_319254
Date	January 1993
Contributors	Li, Hiu-ming., Chinese University of Hong Kong Graduate School. Division of Clinical and Pathological Sciences.
Publisher	Chinese University of Hong Kong
Source Sets	The Chinese University of Hong Kong
Language	English
Detected Language	English
Type	Text, bibliography
Format	print, vii, 88 leaves : ill. (some mounted col.) ; 30 cm.
Rights	Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)