Background: Evidence supports a significant non-linear relationship between alcohol consumption and cardiovascular disease-specific mortality among US adults. Epidemiologic investigations presume that the J/U-shaped distribution is the sum of the detrimental effect of high consumption on other causes of death and the protective effect on coronary heart disease (CHD) morbidity and mortality. Studies demonstrated that heavy alcohol consumption reduces the risk of CHD. However, results have been inconsistent among heavy drinkers. In this study, we investigated the association of heavy alcohol consumption with CHD among different subgroups in the US.
Methods: Data from the 2020 Behavioral Risk Factor Surveillance System (BRFSS) were used. BRFSS is an annual survey of Americans’ health-related risk behaviors, chronic health conditions, and the use of preventive services among the general adult population via self-report. Logistic regression analysis was conducted to determine the association between history of CHD and heavy alcohol consumption. Heavy alcohol use was defined as consuming greater than 14 drinks per week for men and greater than 7 drinks per week for women. The model was adjusted for other risk factors.
Results: A total of 398,656 cases were included. Approximately, 5.67% of the study population reported history of CHD and 6.47% reported heavy alcohol consumption. Overall, the odds of having CHD among heavy alcohol drinkers was 42% less than those who were not heavy alcohol drinkers (adjusted odds ratio): 0.58, 95% confidence interval (CI): (0.50-0.68). Stratified by age, we found that heavy alcohol consumption could be either risk factor or protective factor of CHD or no effect on CHD across different age groups: for 18-24 age group, the odds of having CHD among heavy alcohol drinkers was 25% higher than those who were not heavy alcohol drinkers, OR 1.25 (CI 0.54-2.90); for 25-34 age group, 1.42 (0.94-2.14); for 35-44 age group, 1.04 (0.75-1.43); for 45-54 age group, 0.78 (0.63-0.96); for 55-64 age group, 0.71 (0.62-0.82); for >64 age group, 0.61 (0.55-0.67). Stratified by race, for the male group, the odds of having CHD among heavy alcohol drinkers was 45% lower than those who were not heavy alcohol drinkers, 0.55 (0.46-0.67); for the female group, 0.52 (0.41-0.66). Stratified by race, for the White group, the odds of having CHD among heavy alcohol drinkers was 47% lower than those who were not heavy alcohol drinkers 0.53 (0.49-0.57); for the Black group, 0.44 (0.30-0.66); for the Hispanic group, 0.84 (0.62-1.13); for Other groups, 0.56 (0.41-0.77).
Conclusion: The study findings demonstrate that heavy alcohol consumption is a protective factor for CHD among people aged >44, the older the more protective, but the younger the more risk of having CHD among people aged
| Identifer | oai:union.ndltd.org:ETSU/oai:dc.etsu.edu:asrf-1894 |
| Date | 07 April 2022 |
| Creators | Olagunju, Olajide, Strasser, Sheryl, Cao, Yan, Zheng, Shimin, Ph.D. |
| Publisher | Digital Commons @ East Tennessee State University |
| Source Sets | East Tennessee State University |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | Appalachian Student Research Forum & Jay S. Boland Undergraduate Research Symposium |
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