The aim of the randomized controlled trial was to test the hypothesis that caudal and minimal effective spinal hyperbaric bupivacaine anaesthesia produce similar level of blockade and can be recommended as alternative methods for adult anorectal surgery. The objectives of the study were as follows:
1. To assess caudal blockade in terms of the rate of success, level and duration of sensory and motor block, clinical profile, and quality of anaesthesia.
2. To determine minimal effective dose of spinal hyperbaric bupivacaine in a randomized, double-blinded controlled trial comparing the clinical effects and quality of sensory and motor block of 7.5 mg, 5 mg, and 4 mg doses of spinal hyperbaric bupivacaine.
3. To study the difference of effects of caudal and low-dose spinal hyperbaric bupivacaine blockade with respect to the rate of success, technical characteristics, level and duration of sensory and motor blockade in a randomized controlled trial.
4. To study the effect of caudal and low-dose spinal hyperbaric bupivacaine blockade on changes in mean arterial blood pressure (BP) and heart rate (HR), rate of postoperative complications and quality of anaesthesia according to the patient and medical staff.
Methods. Three separate studies were carried out including 322 adult patients.
(1) Caudal blockade for adult anorectal study, a pilot study (1 st study). During the period of 01.2001-06.2002 56 patients were involved, a single shot caudal block was made with 22G 40 mm needle... [to full text]
| Identifer | oai:union.ndltd.org:LABT_ETD/oai:elaba.lt:LT-eLABa-0001:E.02~2005~D_20051130_141005-65275 |
| Date | 30 November 2005 |
| Creators | Gudaitytė, Jūratė |
| Contributors | Endzinas, Žilvinas, Kaunas University of Medicine |
| Publisher | Lithuanian Academic Libraries Network (LABT), Kaunas University of Medicine |
| Source Sets | Lithuanian ETD submission system |
| Language | Lithuanian |
| Detected Language | English |
| Type | Doctoral thesis |
| Format | application/pdf |
| Source | http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20051130_141005-65275 |
| Rights | Unrestricted |
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