Post-inspiratory braking is the activation of inspiratory muscles during expiration. Although not energetically optimal, it exists for currently unexplained reasons. It has been postulated that post-inspiratory braking exists in order to maintain arterial CO2 content in a tightly regulated band. A computer simulation of the respiratory system incorporating respiratory control, respiratory mechanics, and gas exchange dynamics was developed in order to evaluate the relationship of post-inspiratory braking to arterial CO 2 content. The simulation was driven with pressure signals having varying amounts of post-inspiratory braking. No significant effect upon arterial CO 2 content was found. This suggests that post-inspiratory braking does not exist for the purposes of increasing CO2 exchange in the lungs.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.20296 |
| Date | January 1998 |
| Creators | Prasad, Robin. |
| Contributors | Bates, Jason H. T. (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Engineering (Department of Biomedical Engineering.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001652192, proquestno: MQ50652, Theses scanned by UMI/ProQuest. |
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