AlcellRTMlignin has been used commercially in adhesive preparation and brake pad linings and experimentally in animal feeds to reduce or eliminate diarrheal attacks in farm animals. Our study dealt with elucidating the antibacterial effect of AlcellRTMlignin. It would appear that adsorbance of E. coli cells to AlcellRTMlignin particles is not essential for destruction of the organism. / The antibacterial activity was delayed by the inclusion of Mg 2+ ions in the AlcellRTMlignin filtrate or in the enumeration medium (BHIA). Addition of bile salts to the enumeration medium (BHIA) enhanced the culturability loss of E. coli cells suspended in the filtrate of AlcellRTMlignin. Using FTIR methodology, it appears, that compounds of AlcellRTMlignin affect phospholipid-phospholipid and/or phospholipid-protein interactions in bacterial membranes, causing the patching of membrane phospholipids and proteins. / Additional studies are necessary to evaluate interactions of compounds of AlcellRTMlignin with bacterial cells.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.29807 |
| Date | January 1999 |
| Creators | Sitnikov, Dmitri. |
| Contributors | Idziak, Edmund S. (advisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Natural Resource Sciences.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 001657826, proquestno: MQ54228, Theses scanned by UMI/ProQuest. |
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