This paper deals with prediction of influence of amino acids mutations on protein stability. The prediction is based on different methods of machine learning. Protein mutations are classified as mutations that increase or decrease protein stability. The application also predicts the magnitude of change in Gibbs free energy after the mutation.
Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:363838 |
Date | January 2017 |
Creators | Flax, Michal |
Contributors | Martínek, Tomáš, Musil, Miloš |
Publisher | Vysoké učení technické v Brně. Fakulta informačních technologií |
Source Sets | Czech ETDs |
Language | Czech |
Detected Language | English |
Type | info:eu-repo/semantics/masterThesis |
Rights | info:eu-repo/semantics/restrictedAccess |
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