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The use of hypertonic saline challenge and sputum induction as an assessment tool in clinical studies in paediatric asthma.

Tsang Wing Tai. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2005. / Includes bibliographical references (leaves 132-157). / Abstracts in English and Chinese. / Contents --- p.i / Abstract - English --- p.iv / Abstract - Chinese --- p.vi / Statement of Originality --- p.viii / Acknowledgements --- p.ix / List of Figures --- p.x / List of Tables --- p.xii / Abbreviations --- p.xiii / Chapter Chapter 1: --- Objectives and planning of studies in this thesis --- p.1 / Chapter Chapter 2: --- Literature Reviews / Chapter 2.1 --- Definition of asthma --- p.2 / Chapter 2.2 --- Diagnosis and classification of asthma in children --- p.5 / Chapter 2.3 --- Assessment of asthma in school-age children --- p.7 / Chapter 2.4 --- The use of HSCSI in clinical trial --- p.27 / Chapter 2.5 --- Problems of sputum induction in children --- p.32 / Chapter 2.6 --- Conclusion --- p.34 / Chapter Chapter 3: --- HSCSI - Methodology and Materials / Chapter 3.1 --- Introduction --- p.35 / Chapter 3.2 --- HSCSI - Methodology --- p.37 / Chapter 3.3 --- Protocol for combined HSCSI --- p.45 / Chapter 3.4 --- Practical considerations in HSCSI --- p.49 / Chapter 3.5 --- Expression of airway response --- p.50 / Chapter 3.6 --- Safety issue in HSCSI --- p.52 / Chapter 3.7 --- Approach in our studies --- p.54 / Chapter 3.8 --- Sputum processing --- p.55 / Chapter 3.9 --- Interpretation of sputum differential cell counts --- p.68 / Chapter 3.10 --- Conclusion --- p.73 / Chapter Chapter 4: --- Factors predicting successful sputum induction / Chapter 4.1 --- Introduction --- p.74 / Chapter 4.2 --- Methods --- p.76 / Chapter 4.3 --- Results --- p.80 / Chapter 4.4 --- Discussion --- p.82 / Chapter 4.5 --- Conclusion --- p.88 / Chapter Chapter 5: --- Use of once-daily fluticasone propionate in children with stable asthma -Study on airway inflammatory markers / Chapter 5.1 --- Introduction --- p.89 / Chapter 5.2 --- Methods --- p.92 / Chapter 5.3 --- Results --- p.97 / Chapter 5.4 --- Discussion --- p.101 / Chapter 5.5 --- Conclusion --- p.105 / Chapter Chapter 6 --- Assessment of cough frequency in children with stable asthma -Study on airway inflammatory markers / Chapter 6.1 --- Introduction --- p.106 / Chapter 6.2 --- Cough Monitoring Machine LR 102 --- p.109 / Chapter 6.3 --- Methods --- p.114 / Chapter 6.4 --- Results --- p.119 / Chapter 6.5 --- Discussion --- p.123 / Chapter 6.6 --- Conclusions --- p.127 / Chapter Chapter 7 --- Overall summary and conclusion --- p.128 / References --- p.132 / Appendix I Assessment form 226}0ؤ HSCSI

Identiferoai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_325096
Date January 2005
ContributorsTsang, Wing Tai., Chinese University of Hong Kong Graduate School. Division of Medical Sciences.
Source SetsThe Chinese University of Hong Kong
LanguageEnglish, Chinese
Detected LanguageEnglish
TypeText, bibliography
Formatprint, xiii, 157 leaves : ill. ; 30 cm.
RightsUse of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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