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The effects of high repetition rate stimuli on electrocochleography performed on normal hearing subjects

THE DEPARTMENT OF SPEECH PATHOLOGY AND
AUDIOLOGY. FACULTY OF ARTS, UNIVERSITY OF THE
WITWATERSRAND, JOHANNESBURG
In partial fulfillment of the requirements for the degree of Master of
Arts by coursework in Audiology
June 1999 / High stimulus repetition rates have been proposed as a solution to the poor sensitivity and
specificity of the standard electrocochleogram. The use of this approach has been
confounded, however, by conflicting literature reports on the effects of high stimulus
repetition rates on normal subjects. This study aimed to confirm the effects of high stimulus
repetition rates on normal hearing subjects as a precursor to clinical high stimulus repetition
rate electrocochleography trials. Electrocochleogram tracings were recorded binaurally from
51 normal hearing subjects at 7.1 cps, 51.1 cps, 101.1 cps and 151.1 cps and the
summating potential and action potential latencies and amplitudes, summating
potential/action potential amplitude ratios and waveform widths were recorded. Statistical
analyses showed that increasing the stimulus repetition rate caused statistically (p<O.05) and
clinically (p<O.O1 for latency and p<O.005 for amplitude) significant changes to the action
potential latency and amplitude, summating potential/action potential amplitude ratio and
waveform width, but caused only limited statistical (p<O.05) and clinical (p<O.OI for
latency and p<O.005 for amplitude) changes to the summating potential amplitude and
latency. Subject age had no effect on the results and there was no interaction between age
and stimulus repetition rates. These findings provide the most comprehensive data on the
effects of fast stimulus repetition rates to date, and have provided the beginnings of a valid
clinical normative database for high stimulus repetition rate tympanic electrode
electrocochleography.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/20892
Date17 August 2016
CreatorsBowker, Caren Anne
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeThesis
Formatapplication/pdf

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