In 1947 D.G. Denton (Murray, Denton, Stevenson, and Diena, 1957) isolated a mold, later identified as Penicillium cyaneo-fulvum, and demonstrated that it produced in culture a substance which neutralized staphylococcal alpha-haemolysin. In subsequent work on this toxin-neutralizing agent, Diena (1954 and 1956) developed a method of purifying the toxin-neutralizing substance and established that it neutralized a wide spectrum of bacterial toxins. The toxin neutralizing substance derived from culture filtrates of P. cyaneo-fulvum has been designated Noxiversin. The purpose of this investigation was to study some of the characteristics of the neutralization of staphylococcal alphahaemolysin by Noxiversin.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.111345 |
| Date | January 1957 |
| Creators | Tanner, Charles. E. |
| Contributors | Girvin, G. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Biology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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