During the winter months of 1950-1951 a pneumococcal infection, type 19, broke out among our guinea pigs. Sulfonamide therapy was started immediately; all animals, healthy or sick, receiving one-half grain per pound body weight of sulfamethazine every day in their drinking water. Sera, to be used as complement for the serological laboratory, was always obtained from large healthy guinea pigs. During the pneumococcal outbreak, greater care than ever was taken to see that only healthy animals were used, but in spite of the precautions taken, it soon became evident that the complement was unsatisfactory. In the light of this, it was suggested that an investigation into complement activity during sulfonamide therapy would be of value.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.123978 |
| Date | January 1952 |
| Creators | Johnston, Constance Anne. |
| Contributors | Kalz, G. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Bacteriology.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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