The analysis of survival data with a possible cure fraction has attracted much interest in the last two decades. Various models and estimating methods have been proposed for such data and they have been applied in many fields, especially in cancer clinical trials. In the thesis, we consider some new general cure models, which include existing survival models as their special cases. We also consider a nonparametric estimation of cure rate. The estimator is proved consistent and asymptotically normal. We also consider the application of proportional density for cure data and the analysis of length-biased cure data. / Thesis (Ph.D, Mathematics & Statistics) -- Queen's University, 2012-01-26 09:53:08.127
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OKQ.1974/6976 |
| Date | 26 January 2012 |
| Creators | XU, JIANFENG |
| Contributors | Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.)) |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English, English |
| Detected Language | English |
| Type | Thesis |
| Rights | This publication is made available by the authority of the copyright owner solely for the purpose of private study and research and may not be copied or reproduced except as permitted by the copyright laws without written authority from the copyright owner. |
| Relation | Canadian theses |
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