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Accuracy of activity quantitation of F-18 fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) imaging using simulated malignant tumors

This thesis involves a procedure, which calculated and compared the sum of all the pixel counts, threshold pixel counts sum of a 3D PET image and mean and maximum pixel count of one single transaxial slice (2D) of simulated tumors for a chosen region of interest (ROI). A calibration factor was multiplied by the sum of the pixel counts, threshold pixel counts sum of all the transaxial slices, and the mean, and maximum pixel counts of one single transaxial slice in an ROI to calculate for the activity of the tumor. This activity calculated was compared with the real activity values. The results showed that the sum of all the pixel counts with applied threshold is better to calculate the activity of tumor with greater accuracy.
These findings suggest that a 3D distribution of sum of all the pixel counts was able to calculate the activity of malignant tumors and lung lesions with better accuracy.

Identiferoai:union.ndltd.org:fiu.edu/oai:digitalcommons.fiu.edu:etd-4394
Date24 July 2003
CreatorsDurai, Madhu
PublisherFIU Digital Commons
Source SetsFlorida International University
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceFIU Electronic Theses and Dissertations

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