Submerged cultures of Aspergillus flavus and Aspergillus niger were grown in a medium containing avidin, a substance which serves as an inhibitor of the conversion of acetate to malonate. Control cultures were grown without the addition of avidin.Analysis of the fatty acids produced by cultures grown in a medium containing avidin gave an increase in C16 fatty acids and a decrease in C18 fatty acids, suggesting that malonate plays an important role in the elongation of long chain fatty acids in these organisms. This effect was observed for five to fifteen hours.Evidence of the conversion of palmitate to stearate to oleate to linoleate was presented. That the conversion of oleate to linoleate involves a desaturase which is highly specific is suggested by the observation that, although there are a number of monoenoic acids present in these organisms, the only dienoic acid found was linoleic acid.
| Identifer | oai:union.ndltd.org:BSU/oai:cardinalscholar.bsu.edu:handle/179506 |
| Date | January 1969 |
| Creators | Schwenk, Karl |
| Contributors | Bennett, Alice S. |
| Source Sets | Ball State University |
| Detected Language | English |
| Format | v, 72 leaves : ill. ; 28 cm. |
| Source | Virtual Press |
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