Return to search

Designer peptides to understand the mineralization of calcium salts

Recently, we reported the extraction, purification and amino acid sequence of ansocalcin, the major goose eggshell matrix protein. In vitro studies showed that ansocalcin induces spherical calcite crystal aggregates. We designed two peptides using the unique features of the sequence of ansocalcin and the role of these peptides in CaCO₃ crystallization was investigated. The peptides showed similar activities as compared to ansocalcin, but at a higher concentration. The full characterization of the peptides and a rational for the observed morphology for the calcite crystals are discussed in detail. / Singapore-MIT Alliance (SMA)

Identiferoai:union.ndltd.org:MIT/oai:dspace.mit.edu:1721.1/3779
Date01 1900
CreatorsAjikumar, Parayil Kumaran, Lakshminarayanan, Rajamani, Valiyaveettil, Suresh, Kini, R. Manjunatha
Source SetsM.I.T. Theses and Dissertation
Languageen_US
Detected LanguageEnglish
TypeArticle
Format3117212 bytes, application/pdf
RelationMolecular Engineering of Biological and Chemical Systems (MEBCS);

Page generated in 0.0022 seconds