Class of 2005 Abstract / Objectives: To determine whether acyclovir and cephalexin produced in Mexico are equivalent in content and uniformity to products made in the United States.
Methods: High-pressure liquid chromatography (HPLC) assays were performed on drug samples of Mexican products and U.S. products using U.S. Pharmacopeia – National Formulary (USP-NF) guidelines.5 Content and content uniformity of the products from the U.S. and Mexico were compared.
Results: Acyclovir produced in Mexico had 75.4% content and 78.1% content uniformity compared to the acyclovir produced in the United States. The Mexican manufactured cephalexin had 99.0% content and 99.9% content uniformity compared to the U.S. manufactured cephalexin.
Implications: Not all Mexican manufactured drugs are equivalent in content and content uniformity to American manufactured drugs.
| Identifer | oai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/624765 |
| Date | January 2005 |
| Creators | Nii, Sarah |
| Contributors | Mayersohn, Michael, College of Pharmacy, The University of Arizona |
| Publisher | The University of Arizona. |
| Source Sets | University of Arizona |
| Language | en_US |
| Detected Language | English |
| Type | text, Electronic Report |
| Rights | Copyright © is held by the author. |
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