<p> Three cholic acid derived chelating reagents were
synthesized. They were synthesized by the attachment of
existing chelating ligands onto the side chain of cholic
acid via a spacer chain which connects cholic acid and
chelate. The incorporation of the ligands EDTA, DTPA and
DHPTA onto suitable cholic acid derivatives was performed to
produce the respective cholic acid derivatives: cholic acid
-EDTA, cholic acid-DTPA, and cholic acid-DHPTA. The
synthesis of a fourth chelating reagent was attempted by
attaching HEDTA onto the cholic acid side chain but was
unsuccessful . A complete account of the three syntheses and
one partial synthesis are outlined in this thesis. </p> / Thesis / Master of Science (MSc)
| Identifer | oai:union.ndltd.org:mcmaster.ca/oai:macsphere.mcmaster.ca:11375/19275 |
| Date | 09 1900 |
| Creators | Boag, David |
| Contributors | Bell, R. A., Chemistry |
| Source Sets | McMaster University |
| Language | English |
| Detected Language | English |
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