This masters thesis discusses developments of novel organic methodologies utilizing oxyallyl cationic systems in the pursuit of highly functionalized molecular scaffolds. Chapter 1 focuses on the discovery of the oxyallyl cation intermediate, and examines reported transformations. Detailed optimization and substrate studies following exploitation of a protected 2-oxyallyl cation for nucleophilc capture comprises the information in both Chapter 2 and Chapter 3. Chapter 4 extends methodologies performed by my colleagues and establishes a tandem process using 2-silyloxypentadienyl cations to furnish complex structures. In this report, reaction design and optimization are chronicled, followed by exploration into the reactivity, mechanism, and scope of the developed reactions.
| Identifer | oai:union.ndltd.org:LSU/oai:etd.lsu.edu:etd-10162016-085326 |
| Date | 01 November 2016 |
| Creators | Stepherson, Jacob Reuben |
| Contributors | Kartika, Rendy, Taylor, Carol, Polman, John |
| Publisher | LSU |
| Source Sets | Louisiana State University |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lsu.edu/docs/available/etd-10162016-085326/ |
| Rights | unrestricted, I hereby certify that, if appropriate, I have obtained and attached herein a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to LSU or its agents the non-exclusive license to archive and make accessible, under the conditions specified below and in appropriate University policies, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report. |
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