The role of charge density in polyelectrolyte multilayer coatings used in 2-D cell culture was investigated in this
dissertation. First it is important to comprehend that cells do not attach directly to surfaces, they attach to proteins adhered to
surfaces. Surface charge density in polyelectrolyte films affects not only protein coverage, but also interferes with protein exchange
(Vroman effect), highly charge surfaces favor irreversible absorption of non-adhesive proteins like albumin, which directly affects cell
behavior on these ultrathin films. / A Dissertation submitted to the Department of Chemistry and Biochemistry in partial fulfillment of
the Doctor of Philosophy. / Spring Semester 2016. / April 4, 2016. / Includes bibliographical references. / Joseph B. Schlenoff, Professor Directing Dissertation; Thomas C. S. Keller, University
Representative; Alan Marshall, Committee Member; Hedi Mattoussi, Committee Member.
| Identifer | oai:union.ndltd.org:fsu.edu/oai:fsu.digital.flvc.org:fsu_360314 |
| Contributors | Arias Ramos, Carlos J (authoraut), Schlenoff, Joseph B. (professor directing dissertation), Keller, Thomas C. S. (university representative), Marshall, Alan G. (Alan George) (committee member), Mattoussi, Hedi (committee member), Florida State University (degree granting institution), College of Arts and Sciences (degree granting college), Department of Chemistry and Biochemistry (degree granting department) |
| Publisher | Florida State University |
| Source Sets | Florida State University |
| Language | English, English |
| Detected Language | English |
| Type | Text, text |
| Format | 1 online resource (142 pages), computer, application/pdf |
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