Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005. / Vita. / Includes bibliographical references. / Model studies on the total synthesis of salvilenone, a phenalenone diterpene found in the roots of Salvia miltiorrhiza Bunge, are reported via a double annulation strategy. The key steps in the proposed synthesis involve a regiocontrolled benzannulation involving the photochemical Wolff rearrangement of an a-diazo ketone and an alkoxy acetylene moiety which assembles an aromatic ring in one step from acyclic precursors followed by an intramolecular [4 + 2] cycloaddition of a conjugated enyne and benzyne intermediate. / by HuiWon Choi. / S.M.
| Identifer | oai:union.ndltd.org:MIT/oai:dspace.mit.edu:1721.1/33656 |
| Date | January 2005 |
| Creators | Choi, HuiWon |
| Contributors | Rick L. Danheiser., Massachusetts Institute of Technology. Dept. of Chemistry., Massachusetts Institute of Technology. Dept. of Chemistry. |
| Publisher | Massachusetts Institute of Technology |
| Source Sets | M.I.T. Theses and Dissertation |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | 47 leaves, 1841632 bytes, 1843484 bytes, application/pdf, application/pdf, application/pdf |
| Rights | M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission., http://dspace.mit.edu/handle/1721.1/7582 |
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