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Pulp reactions to a synthetic hydroxyapatite and chlorhexidine in monkeys

Indiana University-Purdue University Indianapolis (IUPUI) / The study compared pulp reactions to a synthetic hydroxyapatite and
to calcium hydroxide with either one percent chlorhexidine or distilled
water as a mixing vehicle. Forty-seven permanent teeth of two monkeys
were mechanically exposed under aseptic conditions. The pulps were then
capped with one of the following: synthetic hydroxyapatite mixed with
chlorhexidine; synthetic hydroxyapatite mixed with water; calcium hydroxide mixed with chlorhexidine; calcium hydroxide mixed with water.
Small square sheets of gold foil were then placed over the capping
material. A base of IRM was placed and the cavities were restored with
amalgam. The teeth were extracted at 14 and 90 days after pulp capping.
The specimens were fixed in 10% formalin and decalcified in 5% formic
acid. Serial sections 7 microns thick were prepared and stained with
hematoxylin and eosin.
The synthetic hydroxyapatite mixed with one percent chlorhexidine
or water was well tolerated by the dental pulp. Complete bridging occurred
infrequently in the specimens capped with the hydroxyapatite, compared
to those capped with calcium hydroxide, which usually showed complete bridging of the exposure.

Identiferoai:union.ndltd.org:IUPUI/oai:scholarworks.iupui.edu:1805/4359
Date January 1980
CreatorsIbarra, Alejandro Javier
Source SetsIndiana University-Purdue University Indianapolis
Languageen_US
Detected LanguageEnglish
TypeThesis

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