Reduction of Propargylic Sulfones to (Z)-Allylic Sulfones using Zinc and Ammonium Chloride.

Description

No / Propargylic sulfones can be cis-hydrogenated using commercial zinc powder and ammonium chloride in THF¿water at room temperature, the major products being the corresponding (Z)-allylic sulfones. Other reducible groups (alkene, benzyloxy) are not affected. Allenylsulfones are implicated in one of the possible reaction pathways.

Links & Downloads

1. Sheldrake, H.M. and Wallace, T.W. (2007). Reduction of Propargylic Sulfones to (Z)-Allylic Sulfones using Zinc and Ammonium Chloride. Tetrahedron Letters. Vol. 48, No. 25, pp. 4407-4411.
2. http://hdl.handle.net/10454/3451
3. https://doi.org/10.1016/j.tetlet.2007.04.099

Tags

Propargylic sulfone

Allylsulfone

cis-Hydrogenation

Reduction

Zinc

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/3451
Date	January 2007
Creators	Sheldrake, Helen M., Wallace, T.W.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, No full-text in the repository