ABSTRACT
Objectives - To compare the osteointegration of plasma sprayed hydroxyapatite (HA) coated and uncoated 5.5 mm cortical screws in equine third metacarpal (MC3) bones in combination with a 4.5mm broad dynamic compression plate (DCP).
Study design - In vivo study.
Animals 6 Adult Thoroughbred horses.
Methods For each horse, four HA coated screws were placed unicortically through a 4.5mm broad DCP in the dorsal cortex of a randomly chosen MC3 bone, with 4 uncoated screws placed in an identical manner in the contralateral MC3 bone. All screws were tightened to a torque of 5.4 N-m. Extraction torques were recorded for the screws when removed after 12 weeks.
The mean extraction torques for HA coated and uncoated screws were compared to insertion torque using a paired ttest with the statistical significance set at p < 0.05.
Results Mean extraction torque of the HA coated screws was significantly (p <0.0002) greater than 5.4 N-m. The mean extraction torque of the uncoated screws was significantly (p < 0.0001) less than 5.4 N-m. The mean extraction torque for the HA coated screws were significantly (p < 0.0001) greater than that of the uncoated screws.
Conclusion - The results suggest that osteointegration was occurring for the HA coated screws. The results also suggest that osteointegration did not take place during the 12 weeks period for the uncoated screws.
Clinical Relevance - The use of plasma sprayed HA coated screws may provide a means of improving the stability of internal fixation of an equine long bone fractures during the entire healing period by promoting osteointegration.
| Identifer | oai:union.ndltd.org:LSU/oai:etd.lsu.edu:etd-06052012-192854 |
| Date | 11 June 2012 |
| Creators | Durham, Myra Elizabeth |
| Contributors | Sod, Gary, Mitchell, Colin, Riggs, Laura |
| Publisher | LSU |
| Source Sets | Louisiana State University |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lsu.edu/docs/available/etd-06052012-192854/ |
| Rights | unrestricted, I hereby certify that, if appropriate, I have obtained and attached herein a written permission statement from the owner(s) of each third party copyrighted matter to be included in my thesis, dissertation, or project report, allowing distribution as specified below. I certify that the version I submitted is the same as that approved by my advisory committee. I hereby grant to LSU or its agents the non-exclusive license to archive and make accessible, under the conditions specified below and in appropriate University policies, my thesis, dissertation, or project report in whole or in part in all forms of media, now or hereafter known. I retain all other ownership rights to the copyright of the thesis, dissertation or project report. I also retain the right to use in future works (such as articles or books) all or part of this thesis, dissertation, or project report. |
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