The growing development of artificial intelligence (AI), particularly neural networks, is transforming applications of AI in healthcare, yet it raises significant privacy concerns due to potential data leakage. As neural networks memorise training data, they may inadvertently expose sensitive clinical data to privacy breaches, which can engender serious repercussions like identity theft, fraud, and harmful medical errors. While regulations such as GDPR offer safeguards through guidelines, rooted and technical protections are required to address the problem of data leakage. Reviews of various approaches show that one avenue of exploration is the adaptation of Generative Adversarial Networks (GANs) to generate synthetic data for use in place of real data. Since GANs were originally designed and mainly researched for generating visual data, there is a notable gap for further exploration of adapting GANs with privacy-preserving measures for generating synthetic text data. Thus, to address this gap, this study aims at answering the research questions of how a privacy-preserving GAN can be adapted to safeguard the privacy of clinical text data and what challenges and potential solutions are associated with these adaptations. To this end, the existing privGAN framework—originally developed and tested for image data—was tailored to suit clinical text data. Following the design science research framework, modifications were made while adhering to the privGAN architecture to incorporate reinforcement learning (RL) for addressing the discrete nature of text data. For synthetic data generation, this study utilised the 'Discharge summary' class from the Noteevents table of the MIMIC-III dataset, which is clinical text data in American English. The utility of the generated data was assessed using the BLEU-4 metric, and a white-box attack was conducted to test the model's resistance to privacy breaches. The experiment yielded a very low BLEU-4 score, indicating that the generator could not produce synthetic data that would capture the linguistic characteristics and patterns of real data. The relatively low white-box attack accuracy of one discriminator (0.2055) suggests that the trained discriminator was less effective in inferring sensitive information with high accuracy. While this may indicate a potential for preserving privacy, increasing the number of discriminators proves less favourable results (0.361). In light of these results, it is noted that the adapted approach in defining the rewards as a measure of discriminators’ uncertainty can signal a contradicting learning strategy and lead to the low utility of data. This study underscores the challenges in adapting privacy-preserving GANs for text data due to the inherent complexity of GANs training and the required computational power. To obtain better results in terms of utility and confirm the effectiveness of the privacy measures, further experiments are required to consider a more direct and granular rewarding system for the generator and to obtain an optimum learning rate. As such, the findings reiterate the necessity for continued experimentation and refinement in adapting privacy-preserving GANs for clinical text.
| Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:su-224010 |
| Date | January 2023 |
| Creators | Nazem, Atena |
| Publisher | Stockholms universitet, Institutionen för data- och systemvetenskap |
| Source Sets | DiVA Archive at Upsalla University |
| Language | English |
| Detected Language | English |
| Type | Student thesis, info:eu-repo/semantics/bachelorThesis, text |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess |
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