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Previous issue date: 2017-12-12 / A sinergia entre a tuberculose e o v?rus da imunodefici?ncia humana (HIV) vem causando grande impacto na epidemiologia da tuberculose nas Am?ricas, seja em pa?ses desenvolvidos ou naqueles em desenvolvimento, configurando um problema emergente em todo o continente. A coinfec??o pelo Micobacterium tuberculosis e o HIV vem sendo estuda em v?rios pa?ses, onde as duas infec??es representam importantes problemas de sa?de p?blica. A infec??o pelo HIV pode ser considerada, um dos principais fatores de risco que faz com que um indiv?duo com tuberculose latente (TBL) desenvolva a tuberculose ativa. Este trabalho teve como objetivo analisar o padr?o da varia??o espacial da incid?ncia de tuberculose (TB) e sua coinfec??o com HIV no estado do Rio Grande do Norte (RN), no per?odo de janeiro de 2001 a dezembro de 2011. A popula??o de estudo constitui-se de todos os casos de TB e da co-infec??o TB/HIV ocorridos no Estado do Rio Grande do Norte, notificados no banco de dados do Sistema de Informa??o de Agravos de Notifica??o (SINAN-MS) no per?do analisado. Para uma an?lise temporal mais consistente, foram constru?dos mapas considerando o tri?nio 2001 ? 2003 e os quadri?nios 2004 ? 2007 e 2008 ? 2011. Informa??es s?cio demogr?ficas foram obtidas com base no censo 2010 ? IBGE em n?vel de munic?pio. Com rela??o a an?lise estat?stica, utilizou-se ferramentas SIG usando o software QGIS vers?o 2.0.1 Dufour (www.qgis.org), t?cnicas de an?lise estat?stica espacial para dados de ?reas usando o software R-System, vers?o 2.15.0 (www.r-project.gov), al?m do SPSS, vers?o 18. A forma padr?o de apresenta??o de dados de ?rea foi feita por meio de mapas tem?ticos referentes ? taxa de incid?ncia (TI), permitindo observar o padr?o de varia??o espacial. Constatou-se uma varia??o temporal com tend?ncia ascendente da coinfec??o TB/HIV, com uma maior incid?ncia na faixa et?ria de 20 a 49 anos, seguida da faixa et?ria ? 50 anos, a forma pulmonar a mais frequente, com predomin?ncia no sexo masculino. Espera-se, que esse estudo possa contribuir com indicadores que ajudem melhorar o direcionamento dos recursos na rotina do tratamento dos coinfectados no Estado do Rio Grande do Norte, Brasil. / The synergy between tuberculosis and human immunodeficiency virus (HIV) has been causing great impact on the epidemiology of tuberculosis in the Americas, whether in developed countries or those in development, setting up an emerging problem across the continent. The co-infection by the Micobacterium tuberculosis and HIV has been studied in several countries, where the two infections represent important problem of public health. HIV infection can be considered one of the main risk factors that makes a person with latent tuberculosis (TBL) develop active tuberculosis. This work had as objective analyze the pattern of spatial variation in the incidence of tuberculosis (TB) and HIV co-infection your in the State of Rio Grande do Norte (RN), from January 2001 to December 2011. The study population consists of all cases of TB and TB/HIV co-infection occurred in the State of Rio Grande do Norte, reported in the database of the information system of reportable diseases (SINAN-MS) in the period analyzed. For a more consistent temporal analysis, maps were constructed considering the triennium 2001-2003 and 2004-2007 quadrennium and 2008-2011. Social and demographic information were obtained based on the 2010 census ? IBGE municipality level. With respect to statistical analysis, we used GIS tools using QGIS version 2.0.1 software Dufour (www.qgis.org), spatial statistical analysis techniques to data of areas using the R-System software, version 2.15.0 (www.r-project.gov ), in addition to the SPSS, version 18. The standard way of presenting data from the area was made by using thematic maps concerning the incidence rate (TI), allowing you to see the pattern of spatial variation. It has a temporal variation with upward trend of co-infection TB/HIV, with a higher incidence in the age group of 20 to 49 years, followed by the age group 50 years ?, the most frequent pulmonary, with predominance in males. It is expected, that this study can contribute to indicators, which help improve the targeting of resources in the routine treatment of Coinfected in the State of Rio Grande do Norte, Brazil.
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.ufrn.br:123456789/24928 |
| Date | 12 December 2017 |
| Creators | Fernandes, Maria Jos? de Britto Costa |
| Contributors | 14076152468, Pessoa, Daniela Mendes da Veiga, 87781484487, Souza, Dyego Leandro Bezerra de, 00902557475, Machado, Fl?via Christiane de Azevedo, 03120675423, Eul?lio, Maria do Carmo, 19131623468, Costa, Iris do C?u Clara |
| Publisher | PROGRAMA DE P?S-GRADUA??O EM CI?NCIAS DA SA?DE, UFRN, Brasil |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Source | reponame:Repositório Institucional da UFRN, instname:Universidade Federal do Rio Grande do Norte, instacron:UFRN |
| Rights | info:eu-repo/semantics/openAccess |
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