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廣義Gamma分配在競爭風險上的分析 / An analysis on generalized Gamma distribution's application on competing risk

存活分析主要在研究事件的發生時間;傳統的存活分析並不考慮治癒者(或免疫者)的存在。若以失敗為事件,且造成失敗的可能原因不止一種,但它們不會同時發生,則這些失敗原因就是失敗事件的競爭風險。競爭風險可分為有參數的競爭風險與無母數的競爭風險。本文同時考慮了有治癒與有參數的混合廣義Gamma分配,並將預估計的位置參數與失敗機率有關的參數與解釋變數結合,代入Choi及Zhou(2002)提出的最大概似估計量的大樣本性質。並考慮在治癒情況下,利用電腦模擬來估計在型一設限及無訊息(non-informative)的隨機設限(random censoring)下之一個失敗原因與兩個失敗原因下的參數平均數與標準差。 / The purpose of survival analysis is aiming to analyze the timeline of events. The typically method of survival analysis don’t take account of the curer (or the immune). If the event is related to failure and there are more than one possible reason causing the failure but are not happening at the same time, we called the possible reasons a competing risk for failed occurrence. competing risk can be categorized as parameter and non-parameter. This research has considered the generalized gamma distribution over both cure and parameter aspects. In addition, it combines anticipated parameter with covariate which affected to the possibilities of failure. Follow by the previous data, it is then substituted by the large-sample property of the maximum likelihood estimator which is presented by Choi and Zhou in 2002. With considering the possibilities of cure, it uses computer modeling to investigate that under the condition of type-1 censoring and non-informatively random censoring, we will find out the parameter mean and standard error that is resulted by one and two reason causes failure.

Identiferoai:union.ndltd.org:CHENGCHI/G0096354022
Creators陳嬿婷
Publisher國立政治大學
Source SetsNational Chengchi University Libraries
Language中文
Detected LanguageEnglish
Typetext
RightsCopyright © nccu library on behalf of the copyright holders

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