Pigs, mice and human beings are all vertebrate mammals. More than 90% of genomes in pigs and mice are the same as human beings. Experiment pigs and mice are with advantages in purebloods, small size, high reproductive capacity and short life cycle, etc. The tissue structure and metabolism of physiology in pig and mice are similar to human as well. Therefore, laboratory pigs and mice are often used to substitute human beings for biomedical engineering test. The research topics of this thesis are in the area of biomechanical properties of bones in mammal. The objectives of the study are to reveal the biomechanical properties of various types of bones and discuss its implication to human development.
The entire thesis is divided into three parts. The first topic used micro-indentation test and FEM analysis for the determination of biomechanical properties of controlled cartilages in pigs. The second topic applied (a) three-point-bend failure test to study the age-related radius strength in mice, (b) tensile test to study the mechanical response of cranial sutures in mice, and (c) optical interferometry for 3D profile determination of mouse cranium. The third topic is for quantitative analysis of patterns in cranial sutures using DFT (Discrete Fourier Transform).
The mechanism of diseases (such as osteoporosis, craniosynostosis, etc.) and the complexity of patterns in human cranial sutures in different age groups are discussed.
| Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0117107-154949 |
| Date | 17 January 2007 |
| Creators | Wu, Yii-der |
| Contributors | Ying-chien Tsai, Jao-hwa Kuang, Ming-hwa R. Jen, T. N. Shiau, Yuh J. Chao, T. Y. Chen, Shou-shing Hsieh, Chi-hui Chien |
| Publisher | NSYSU |
| Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0117107-154949 |
| Rights | unrestricted, Copyright information available at source archive |
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