Yes / We describe a concise and straightforward approach to the total syntheses of (+)-Strictifolione and Cryptofolione in the longest linear sequences of four steps and six steps from 3-phenyl propanal and trans-cinnamaldehyde, respectively. The route utilized a titanium tetraisopropoxide/(R)-[1,1'-binaphthalene]-2,2'-diol catalyzed Mukaiyama aldol reaction, indium(0)-promoted Barbier reaction, and olefin cross-metathesis as the key reactions. / National Science Foundation of China [21062088, 21562020, and 21462004], the Science and Technology Plan Project of Jiangxi Province [No. 20151BBG70028, 20142BBE50006] and State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources [CMEMR2014-A04] for the funding support.
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/17850 |
| Date | 26 May 2020 |
| Creators | Li, X., Wang, G., Zhang, Z., Wu, Na, Yang, Q., Huang, S., Wang, X. |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Accepted manuscript |
| Rights | © 2019 Taylor & Francis. This is an Author's Original Manuscript of an article published by Taylor & Francis in Synthetic Communications on 16 Mar 2019 available online at https://doi.org/10.1080/00397911.2019.1580373, Unspecified |
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