Thesis advisor: Marc L. Snapper / Chapter 1: The design of a novel first aid smart fabric that is linked to a biologically active molecule through an event specific cleavable linker is described. Successful functionalization of a cellulose filter paper fabric mimic and the synthesis of a linker which is potentially selectively cleavable in the presence of blood have been achieved. Chapter 2: Synthetic studies towards the total synthesis of Torilin, a sesquiterpene guaiane natural product with interesting biological activities are described. The synthesis of the hydroazulene core of Torilin is accomplished through a cyclopropanation/ Lewis acid mediated fragmentation of a highly functionalized polycyclic system which is rapidly accessed through the intramolecular cycloaddition of cyclobutadiene. / Thesis (MS) — Boston College, 2013. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Chemistry.
| Identifer | oai:union.ndltd.org:BOSTON/oai:dlib.bc.edu:bc-ir_101188 |
| Date | January 2013 |
| Creators | Lando, Alisa |
| Publisher | Boston College |
| Source Sets | Boston College |
| Language | English |
| Detected Language | English |
| Type | Text, thesis |
| Format | electronic, application/pdf |
| Rights | Copyright is held by the author, with all rights reserved, unless otherwise noted. |
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