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Vliv klíštěcích slin na replikaci viru klíšťové encefalitidy \kur{in vitro} a vliv klíštěcích cystatinů na genovou expresi interferon regulačních faktorů / The influence of tick saliva on the replication of tick-borne encephalitis virus \kur{in vitro} and the influence of tick cystatins on gene expression of interferon regulated factors

This study was focused on the influence of hard tick from Ixodes ricinus on the replication of tick-borne encephalitis virus in vivo and the on the accompained changes in the levels of inflammatory cytokines which were determined in serum of infected mice. Futher the effect of tick cystatins, the inhibitors of cysteine proteases, on gene expression of interferon regulated factors was investigated in dendritic cells upon stimulation with Toll-like receptor ligands.

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:135724
Date January 2012
CreatorsŠIRMAROVÁ, Jana
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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