Objectives: Azithromycin is a second-generation macrolide active against a wide range of bacteria, including obligate anaerobes implicated as bacterial pathogens in human periodontitis. Clinical studies indicate short-term systemic azithromycin therapy to be beneficial in the treatment of acute periodontal abscesses and as an adjunct to mechanical periodontal therapy of periodontitis patients. Only sparse recent data is available on the susceptibility or resistance of putative periodontal bacterial pathogens to azithromycin, particularly among subgingival isolates from periodontitis patients residing in the United States. Thus, the present degree to which major periodontal bacterial pathogens in United States periodontitis patients exhibit resistance to azithromycin is not known. As a result, the purpose of the present study was to determine the prevalence of in vitro resistance to azithromycin, as compared to metronidazole, among selected red/orange complex periodontal pathogens isolated from severe periodontitis patients in the United States. / Oral Biology
| Identifer | oai:union.ndltd.org:TEMPLE/oai:scholarshare.temple.edu:20.500.12613/7695 |
| Date | January 2022 |
| Creators | Vayner, Regina |
| Contributors | Rams, Thomas E., Page, Lawrence, Whitaker, Eugene J. |
| Publisher | Temple University. Libraries |
| Source Sets | Temple University |
| Language | English |
| Detected Language | English |
| Type | Thesis/Dissertation, Text |
| Format | 41 pages |
| Rights | IN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available., http://rightsstatements.org/vocab/InC/1.0/ |
| Relation | http://dx.doi.org/10.34944/dspace/7667, Theses and Dissertations |
Page generated in 0.0023 seconds