Objective: The aim of this study was to research the efficacy of Povidone (PVP) Iodine as an adjunct to scaling and root planing (SRP) in reducing periodontal pocket depth (PPD) compared to scaling and root planing with water, saline, or no rinse in the treatment of chronic periodontitis among adult patients. Material and methods: An electronic search of the databases PubMed, EMBASE, Cochrane Library, Medline, and Dentistry & Oral Sciences Source (DOSS) were performed from 2010 up to January 2022. A single reviewer identified and selected screened abstracts and titles for possible inclusion, and assessed randomized, controlled clinical trials comparing the additional benefit of PVP-Iodine in the treatment of chronic periodontitis in adult patients. A meta-analysis was conducted to analyze the eight studies included.
Results: The pool effects for split mouth design and randomized control trials was significant in favoring the control group. A mean reduction of periodontal pocket depth (PPD) favoring the control group was observed, this reduction was 0.93 mm, (95% CI: 0.66–1.2) (p = 0.00, fig. 2a) for split mouth design studies and a reduction of 0.61 mm, (95% CI: 0.2-1.02) (p=0.004, fig. 2b) for randomized controlled trials (RCTs). There was significant heterogeneity between the split mouth studies and RCTs, i2 = 89.7 and i2 = 83.9, respectively. The studies included administered different concentrations and irrigation frequencies of PVP-iodine, presented with different baseline pocket depths, and evaluated different teeth. Based on the studies included, there was no additional benefit of adjunct use of PVP-iodine with SRP in improving PPD reduction.
Conclusion: The adjunctive use of PVP-iodine during scaling and root planing does not improvement pocket depth reduction. However, due to the high heterogeneity between studies more clinical trials should be conducted to evaluate PVP-iodine efficacy in deeper pockets. / Oral Biology
| Identifer | oai:union.ndltd.org:TEMPLE/oai:scholarshare.temple.edu:20.500.12613/7734 |
| Date | January 2022 |
| Creators | Flys, Vladimir |
| Contributors | Seyedain, Merriam, Chialastri, Susan M., Tellez Merch�n, Marisol |
| Publisher | Temple University. Libraries |
| Source Sets | Temple University |
| Language | English |
| Detected Language | English |
| Type | Thesis/Dissertation, Text |
| Format | 27 pages |
| Rights | IN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available., http://rightsstatements.org/vocab/InC/1.0/ |
| Relation | http://dx.doi.org/10.34944/dspace/7706, Theses and Dissertations |
Page generated in 0.0023 seconds