Investigations into the function of mesenchymal-TG2 in epidermal formation and keratinocytes migration were established with varying success using coculture systems. Results indicate TG2 overexpression increases the rate of keratinocytes migration via an as yet unidentified soluble factor. Conversely, the presence of fibroblasts overexpressing this TG have demonstrated an inhibitory effect on keratinocyte migration.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:583516 |
| Date | January 2005 |
| Creators | Rosser-Davies, Sally Jean |
| Publisher | Cardiff University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://orca.cf.ac.uk/54103/ |
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