Ko Ka Lung. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2006. / Includes bibliographical references. / Abstracts in English and Chinese. / Title page --- p.i / Abstract (English) --- p.ii / Abstract (Chinese) --- p.iii / Acknowledgement --- p.iv / Declaration --- p.v / Table of Content --- p.vi / List of Figure --- p.viii / Chapter 1. --- INTRODUCTION --- p.1 / Chapter 1.1 --- Matrix-assisted Laser Desorption / Ionization (MALDI) --- p.2 / Chapter 1.1.1 --- Evolution of Matrix-assisted laser desorption / ionization (MALDI) --- p.2 / Chapter 1.1.1.1 --- Lasers --- p.3 / Chapter 1.1.1.2 --- Matrices --- p.3 / Chapter 1.1.1.3 --- Sample preparation --- p.4 / Chapter 1.1.1.4 --- Desorption --- p.6 / Chapter 1.1.1.5 --- Ionization --- p.7 / Chapter 1.2 --- Fourier Transform Ion Cyclotron Resonance Mass Spectrometry with MALDI (FTICR-MS) --- p.9 / Chapter 1.2.1 --- History of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry --- p.9 / Chapter 1.2.2 --- Basics of FTICR-MS --- p.11 / Chapter 1.2.3 --- FTICR couple with external ionization source --- p.15 / Chapter 1.2.4 --- Coupling of MALDI to FTICR --- p.16 / Chapter 1.3 --- Problems encountered on the coupling of MALDI to FTICR-MS --- p.17 / Chapter 1.4 --- Outline of present work --- p.19 / Chapter 2 --- SIMULATION METHOD --- p.20 / Chapter 2.1 --- Overview of the ion optics simulation --- p.21 / Chapter 2.2 --- History of SIMION Program --- p.22 / Chapter 2.3 --- Basics and theory of SIMION version 6.0 --- p.24 / Chapter 2.4 --- Simulation method --- p.26 / Chapter 2.4.1 --- Creating potential array --- p.27 / Chapter 2.4.2 --- User program --- p.29 / Chapter 2.4.3 --- Ion definition parameter --- p.31 / Chapter 2.4.4 --- Trajectories quality panel --- p.33 / Chapter 2.4.5 --- Data recording --- p.36 / Chapter 3 --- OPTIMIZATION OF RF-ONLY HEXAPOLE UNDER PULSE GAS CONDITION --- p.37 / Chapter 3.1 --- Introduction --- p.38 / Chapter 3.2 --- Simulation conditions --- p.39 / Chapter 3.3 --- Results and discussion --- p.40 / Chapter 3.3.1 --- rf-frequency (w) --- p.41 / Chapter 3.3.2 --- rf voltage (Vo-p) --- p.44 / Chapter 3.3.3 --- Pulse gas pressure(po) --- p.47 / Chapter 3.3.4 --- Trapping potential (VT) --- p.49 / Chapter 3.3.5 --- Effect of space charge --- p.53 / Chapter 3.4 --- Conclusions --- p.60 / Chapter 4 --- OPTIMIZATION OF DIFFERENT HEXAPOLE-BASED INTERFACES FOR PRE-TRAPPING COOLING --- p.61 / Chapter 4.1 --- Introduction --- p.62 / Chapter 4.2 --- Simulation conditions --- p.63 / Chapter 4.3 --- Results and discussion --- p.66 / Chapter 4.3.1 --- Static medium pressure interface --- p.66 / Chapter 4.3.1.1 --- Effect of pressure --- p.66 / Chapter 4.3.1.2 --- Effect of space charge --- p.70 / Chapter 4.3.2 --- Differential pressure model (Skimmer-based) --- p.73 / Chapter 4.3.2.1 --- Effect of pressure --- p.73 / Chapter 4.3.2.2 --- Effect of space charge --- p.76 / Chapter 4.3.3 --- A comparison of the optimal operating conditions for the three proposed interfaces --- p.81 / Chapter 4.3.4 --- Comparison of the theoretical results amd the experimental results --- p.83 / Chapter 4.4 --- Conclusion --- p.84 / Chapter 5 --- CONCLUSIONS --- p.85 / Chapter 5.1 --- Conclusions --- p.86 / REFERENCES --- p.R1 / APPENDIX --- p.A1
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_325515 |
| Date | January 2006 |
| Contributors | Ko, Ka Lung., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, 1 v. (various pagings) : ill. (some col.) ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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