Faculty of Health Sciences,
Degree of Master in Medicine.
9713161h / Introduction: Numerous studies have confirmed the association between the delivered
dose of haemodialysis and patients outcomes. There is thus some evidence regarding the
relationship between dialysis dose and quality of life.
Objective: The study was designed to assess dialysis adequacy using urea kinetic
modelling parameters and to determine the association between dialysis dose and patient
outcomes.
Methods: A retrospective review of the demographic and biochemical data of 61 patients
on chronic haemodialysis in the year 2003 was performed and a prospective component
was added to the study for quality of life and evaluation of cardiovascular comorbidity.
Results: The mean delivered dose Kt/V was 1.34 ± 0.25. There was a statistically
significant correlation (p<0.05) between dialysis dose and the following parameters:
haemoglobin, physical dimension and its 3 scales, the SF-36 overall score, as well as
between dialysis dose and sepsis.
Conclusion: The dialysis dose correlated with a significant number of parameters
including Hb and the physical components of the SF-36; hence, the importance of
measuring the delivered dialysis dose of patient on maintenance dialysis in accordance
with DOQI guidelines for improved patient outcomes is confirmed.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/1866 |
| Date | 17 November 2006 |
| Creators | Jules, Kabahizi |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | 773694 bytes, application/pdf, application/pdf |
Page generated in 0.0025 seconds