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Left atrial strain and 3-dimensional volume measurements of the left atrium : alternative methods for detecting diastolic dysfunction / Vänster förmaksstrain och 3D mätning av vänster förmaksvolym : alternativa metoder för att detektera diastolisk dysfunktion

Heart failure with preserved ejection fraction has its main pathophysiology in the diastolic dysfunction which is characterized by increased filling pressures. This can be discovered during a routinely performed echocardiographic examination. In 2016 the American Society of Echocardiography published a recommendation to simplify the assessment of diastolic dysfunction. Whether or not these recommendations have simplified the gradings is questionable. Left atrial strain has been shown to decrease in the absent of diastolic dysfunction and 3D echocardiographic volume measurements of the left atrium has been showing more accurate volumes of the heart compared to 2D-measurements. A quantitative study was therefore made to compare the results from the recommended algorithm with the two methods - left atrial strain and 3D-measurements of the left atrium volume. A total of 138 women and men were included with the data collected both prospective and retrospective. The aim with this quantitative study was to examine if LA-strain and 3D volume measurements of the left atrium can be useful parameters to use in detecting diastolic dysfunction in future recommendations. The result showed significant differences (p<0.05) in LA-strain between normal diastolic function and grade 2 and -3. Also, between grade 1 and grade 2- and 3. Between undetermined diastolic function there was a statistical difference with grade 2- and 3. LA-strain showed a significant negative correlation between E/é and 2D. LA-strain and 3D-measurements of the left atrium can be useful tools in the next recommendations of grading diastolic dysfunction.

Identiferoai:union.ndltd.org:UPSALLA1/oai:DiVA.org:uu-495379
Date January 2022
CreatorsNilsson, Fanny
PublisherUppsala universitet, Institutionen för kvinnors och barns hälsa
Source SetsDiVA Archive at Upsalla University
LanguageEnglish
Detected LanguageEnglish
TypeStudent thesis, info:eu-repo/semantics/bachelorThesis, text
Formatapplication/pdf
Rightsinfo:eu-repo/semantics/openAccess

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