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Mathematical Modeling of Type 1 Diabetes

Type 1 Diabetes (T1D) is an autoimmune disease where the pancreas produces little to no insulin, which is a hormone that regulates blood glucose levels. This happens because the immune system attacks (and kills) the beta cells of the pancreas, which are responsible for insulin production. Higher levels of glucose in the blood could have very negative, long term effects such as organ damage and blindness.
To date, T1D does not have a defined cause nor cure, and research for this disease is slow and difficult due to the invasive nature of T1D experimentation. Mathematical modeling provides an alternative approach for treatment development and can greatly advance T1D research. This thesis describes both a single-compartment and multi-compartment model for Type 1 Diabetes.

Identiferoai:union.ndltd.org:CLAREMONT/oai:scholarship.claremont.edu:hmc_theses-1228
Date01 January 2019
CreatorsWu, Gianna
PublisherScholarship @ Claremont
Source SetsClaremont Colleges
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceHMC Senior Theses
RightsGianna Wu, default

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