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Srovnání adherence a úspěšnosti antiretrovirové léčby virové hepatitidy C u uživatelů a neuživatelů drog / Comparison of adherence and outcome of antiviral therapy of viral hepatitis C in drug users and non-users

3456 ABSTRACT: Background: VHC is a widespread serious chronic infectious disease. Most of the patients affected by the disease consist of IDUs. Treatment of VHC is now perceived as an important preventive element for the spread of the disease in IDUs population. Adherence to treatment is absolutely crucial for the successful completion of treatment. Adherence to treatment is often questioned by clinicians who treat VHC in patients using addictive substances. Objectives: To compare the efficacy of treatment of VHC in patients with a history of drug in patients without a history of drug, to compare treatment adherence among patients without a drug history and patients with drug history, to map out the factors affecting adherence to treatment and to find a place in the therapeutic team for expertise of addictologist. Material and Methods: Data from documentation of 258 patients that were treated in 2006- 2015 for viral hepatitis C at the Department of Infectious Diseases at the University Hospital Brno have been processed with using the statistical and analytical methods and in compliance with ethical rules retrospectively. Adherence to treatment (defined as the completion or early termination of treatment due to non-compliance with the treatment regime by the patient) and the effectiveness of treatment, as...

Identiferoai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:343269
Date January 2016
CreatorsVěchetová, Sonja
ContributorsMravčík, Viktor, Janíková, Barbara
Source SetsCzech ETDs
LanguageCzech
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/masterThesis
Rightsinfo:eu-repo/semantics/restrictedAccess

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