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Association Between Obesity and Therapeutic Goal Attianment in Patients with Concomitant Hypertension and Dyslipidemia

Objective: A retrospective study was conducted to examine the variations in therapeutic {blood pressure (BP) and lipid} goal attainment and medication utilization pattern in patients with concomitant hypertension and dyslipidemia, specifically comparing obese versus non-obese patients. Methods: GE Centricity EMR database containing data from 2004-2011 was utilized. 9,086 patients diagnosed with concomitant hypertension and dyslipidemia were evaluated. Goal attainment and treatment pattern for BP and lipid levels was assessed based on JNC 7 and NCEP ATP III guidelines, respectively. Results: Substantial proportion of patients with concomitant hypertension and dyslipidemia failed to attain BP and lipid goals. Further, in patients with concomitant hypertension and dyslipidemia, obesity appears to be an independent risk factor for the failure to attain BP and dual BP/LDL-C. Conclusions: With increasing prevalence of obesity and inadequate therapeutic goal attainment in these populations, healthcare professionals should use appropriate treatment strategies for improving the management of cardiovascular risk factors (hypertension, dyslipidemia, and obesity). / Mylan School of Pharmacy and the Graduate School of Pharmaceutical Sciences / Pharmacy Administration / MS / Thesis

Identiferoai:union.ndltd.org:DUQUESNE/oai:digital.library.duq.edu:etd/154155
Date17 July 2014
CreatorsChopra, Ishveen
ContributorsKhalid M. Kamal, Sean D. Candrilli, Gibbs Kanyongo
Source SetsDuquesne University
Detected LanguageEnglish
RightsTwo year embargo: no access to PDF file until release date by author request.

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