The effect of hemodynamics on cardiovascular disease (CVD) is very important since
CVD is the number one killer nationwide and around the globe. Coronary artery disease (CAD),
also called arteriosclerosis, is a common disease found in human arteries, including coronary
arteries and the common carotid artery. The abdominal aorta is also affected by atherosclerotic
aneurysm.
Formation of atherosclerosis obstructs the blood flow in arteries and changes the
hemodynamics pattern. Numerical and experimental modeling in a tapered artery using turbulent
models has been untouched so far. To investigate the cause of atherosclerosis and atherosclerotic
aneurysm, simulations were done using the finite volume method via FLUENT 6.3.26.
Wilcox’s two-equation standard κ-ω model was used for numerical simulation of a
tapered artery and abdominal aortic aneurysm. The tapered artery had a diameter reduction of 25
percent at the stenosed area. The two-equation turbulence κ-ω model was employed on a
geometry to validate the numerical results with velocity profiles of experimental results. Blood
was assumed to be Newtonian in all simulations.
The main objectives of this thesis were as follows:
1. To study the shear stress and blood streamlines of tapered artery at different Reynolds
number using the κ-ω model.
2. To simulate the pulsatile flow conditions on a tapered artery and abdominal aortic
aneurysm.
3. To predict and validate the kick-start of atherosclerosis based on hemodynamic
conditions.
4. To study the effect of turbulent viscosity on shear stress. / Thesis (M.S.)--Wichita State University, College of Engineering, Dept. of Aerospace Engineering.
| Identifer | oai:union.ndltd.org:WICHITA/oai:soar.wichita.edu:10057/3751 |
| Date | 12 1900 |
| Creators | Tala, Chiragkumar D. |
| Contributors | Hoffmann, Klaus A. |
| Publisher | Wichita State University |
| Source Sets | Wichita State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis |
| Format | xvi, 99 leaves, ill. |
| Rights | Copyright Chiragkumar D. Tala, 2010. All rights reserved |
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