archives@tulane.edu / Reactive case detection (RCD) for malaria is a surveillance strategy in which the detection of a malaria case by passive surveillance triggers a search for more cases in and around the household of the passively detected case (index household). RCD is currently used in Zanzibar as part of their elimination strategy. This research aimed to evaluate RCD as a surveillance strategy in Zanzibar and consists of a rolling cross-sectional survey and a systems-effectiveness and cost analysis. In the survey, research staff attend RCD investigations to administer a household questionnaire and test all household members for malaria. In the systems-effectiveness and costing component of the study the systems-effectiveness and cost of the RCD is assessed and compared with hypothetical variants of the system. The studies found that, in Zanzibar, infection prevalence is higher within index households than in neighboring households. Nonetheless, while malaria infection exists at higher prevalence amongst co-habitants of passively detected cases in Zanzibar, RCD as implemented does not have the ability to detect the majority of them. This is due, primarily, to the lack of sensitivity of the RDT to detect low-density infections and, secondarily, to the low level of investigation following a case report. / 1 / Logan Stuck
| Identifer | oai:union.ndltd.org:TULANE/oai:http://digitallibrary.tulane.edu/:tulane_119688 |
| Date | January 2020 |
| Contributors | Stuck, Logan (author), Yukich, Joshua (Thesis advisor), School of Public Health & Tropical Medicine Tropical Medicine (Degree granting institution) |
| Publisher | Tulane University |
| Source Sets | Tulane University |
| Language | English |
| Detected Language | English |
| Type | Text |
| Format | electronic, pages: 101 |
| Rights | No embargo, Copyright is in accordance with U.S. Copyright law. |
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