Background
HIV is a risk factor for empyema. HIV-infected patients with empyema appear to have worse outcomes. This study assessed whether HIV infection affected aetiology or outcomes of patients with empyema.
Methods A retrospective study of patients with empyema admitted to CHBAH from January 2006 to December 2009 was conducted. HIV-infected and non-infected patients were evaluated for differences in aetiology and outcomes. Sub-analysis according to CD4 counts and antiretroviral use in HIV-infected patients was performed.
Results
0f 172 patients, 125 (73%) were HIV-infected. HIV infected patients with lower CD4 counts were more often diagnosed with clinical tuberculosis (p<0.05). Aetiology of empyema was frequently not determined in HIV non-infected patients (p<0.05). More patients on antiretrovirals underwent thoracic surgery (p<0.05) and had shorter hospital stays than those not on antiretrovirals (p<0.05).
Conclusions No differences in empyema aetiology among HIV-infected versus non-infected patients were found. Antiretroviral use was associated with improved outcomes.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/12488 |
| Date | 05 March 2013 |
| Creators | Kaye-Eddie, Grace Helga |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | application/pdf |
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