Design and development of novel one-step reactions that produce nitrogen-containing scaffolds is an invaluable area of chemistry due to the abundance of these moieties in natural products and biologically active molecules. Discovering novel methods using uncommon substrates and rare earth metals to access these significant scaffolds present a challenge. Over the course of my doctoral studies, I have designed, developed and optimized novel reactions by using rarely known substrates and rare earth metals that have afforded important nitrogen-containing scaffolds. The products obtained allow access to otherwise long-to-synthesize molecules and expeditious construction of biologically active molecules.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc2137562 |
| Date | 05 1900 |
| Creators | Cortes Vazquez, Jose |
| Contributors | Slaughter, LeGrande M., Wang, Hong, Cundari, Thomas, Dandekar, Sushama, Gevorgyan, Vladimir |
| Publisher | University of North Texas |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | Text |
| Rights | Public, Cortes Vazquez, Jose, Copyright, Copyright is held by the author, unless otherwise noted. All rights Reserved. |
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