Background: The human Aldoketoreductase 1B10 gene (AKR1B10) encodes one of the enzymes belonging to the family of aldoketoreductases and may be involved in detoxification of nutrients during digestion. Further, AKR1B10 mRNA (messenger ribonucleic acid) expression was diminished in brain regions potentially involved in the
regulation of eating behavior in rats which are more sensitive to cocaine and alcohol. We hypothesized that the human AKR1B10 gene may also play a role in the regulation of human eating behavior.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa.de:bsz:15-qucosa-169923 |
| Date | 25 March 2015 |
| Creators | Rohde, Kerstin, Federbusch, Martin, Horstmann, Annette, Keller, Maria, Villringer, Arno, Stumvoll, Michael, Tönjes, Anke, Kovacs, Peter, Böttcher, Yvonne |
| Contributors | Universität Leipzig, Integriertes Forschungs- und Behandlungszentrum (IFB) AdipositasErkrankungen, Max-Planck-Institut für Neuro- und Kognitionswissenschaften,, Universität Leipzig, Medizinische Fakultät, Universität Leipzig, Tagesklinik für kognitive Neurologie, BioMed Central, |
| Publisher | Universitätsbibliothek Leipzig |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | doc-type:article |
| Format | application/pdf |
| Source | BMC Genetics 2015, 16 (31) |
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