Pyrrolisoquinoline (B) is found as a major structural motif of the erythrina alkaloid group of natural products. We recognised that a suitably substituted bicyclic lactam (A) could act as a precursor in an intramolecular N-acyliminium mediated cyclisation reaction in a stereoselective approach to the core of the erythrinane target ring system.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:289121 |
| Date | January 2003 |
| Creators | James, Stella L. |
| Publisher | Loughborough University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | https://dspace.lboro.ac.uk/2134/12922 |
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