Early qualitative erythrocyte permeability studies (Gryns, 1896; Hedin, 1897) revealed the wide range of non-electrolyte permeability rates across a cell membrane composed of lipid molecules. Theoretically, water-soluble non-electrolytes such as glycerol, ethylene glycol and erythritol would penetrate less rapidly than lipid-soluble non-electrolytes. It was thought that the rate of penetration of water-soluble non-electrolytes was inversely proportional to their molecular size and the penetration of lipid-soluble non-electrolytes was directly proportional to their lipid-solubility.
Identifer | oai:union.ndltd.org:pacific.edu/oai:scholarlycommons.pacific.edu:uop_etds-2735 |
Date | 01 January 1971 |
Creators | McClure, Joseph Doyle |
Publisher | Scholarly Commons |
Source Sets | University of the Pacific |
Detected Language | English |
Type | text |
Format | application/pdf |
Source | University of the Pacific Theses and Dissertations |
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