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Construction of a Spider Comparative Genomic Database for Analyzing the Araneae Tree of Life

Spiders are one of the most diverse clades of multicellular life on earth, and their success has been attributed to several key genomic features, such as weaving silk, deploying various forms of venom, and being able to metabolize many types of prey. We have created a database of whole genome information from ten spider species from across major branches of the spider tree of life to help contextualize the genomic events occurring along the evolutionary history of the spider clade. Genes from these ten spiders were clustered into gene families which were used to detect duplications, losses, and evidence of selection (dN/dS) along the branches of these spiders' phylogeny. These results also allow us to weigh in on a contentious taxonomic placement for one of these spiders, the Uloborus diversus, which we found to be paraphyletic with other orb-web weaving spiders. One future applications of this database will involve phenotype reconstruction, with the goal of forging a genotype to phenotype map. / Biology

Identiferoai:union.ndltd.org:TEMPLE/oai:scholarshare.temple.edu:20.500.12613/7190
Date January 2021
CreatorsMiraszek, John Louis
ContributorsLiberles, David A., Hey, Jody
PublisherTemple University. Libraries
Source SetsTemple University
LanguageEnglish
Detected LanguageEnglish
TypeThesis/Dissertation, Text
Format70 pages
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Relationhttp://dx.doi.org/10.34944/dspace/7169, Theses and Dissertations

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