Exploring the genetic landscape of complex diseases using the recessive model

Description

High-throughput sequencing technologies have changed the way we identify, study and understand the role of rare variation in Mendelian diseases. Sequencing in complex diseases have proven to be more challenging to interpret, but methods and approaches are being developed to aid in our understanding of variation in these diseases.

Links & Downloads

1. Lim, Teng Ting. 2014. Exploring the genetic landscape of complex diseases using the recessive model. Doctoral dissertation, Harvard University.
2. http://dissertations.umi.com/gsas.harvard:11490
3. http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274464

Tags

Genetics

complex disease

exome sequencing

rare variant

recessive

Additional Fields

Identifer	oai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/12274464
Date	04 June 2016
Creators	Lim, Teng Ting
Contributors	Daly, Mark Joseph
Publisher	Harvard University
Source Sets	Harvard University
Language	en_US
Detected Language	English
Type	Thesis or Dissertation
Rights	open