Purpose Two new scales, CORECTS and PUQE-24 are introduced and validated, and the
safety and effectiveness of Proctofoam-HC® in pregnancy is demonstrated.
Method 315 of Motherisk NVP patients provided information on five clinical parameters
as well as PUQE scores. 28 patients visiting a proctologist were graded for the severity of
anal conditions by a proctologist before administering CORECTS. Pre and postnatal
interviews were conducted with 204 pregnant women prescribed Proctofoam-HC®.
Results Strong correlations were found between the following:
PUQE-24 scores and parameters of well-being, hospitalization, and multivitamin intake;
bleeding and pain components of CORECTS and the proctologist’s grade.There was no
significant difference between mean birth weight of Proctofoam-HC® treated and
comparison groups. There was a significant reduction in all symptoms of hemorrhoids.
Conclusion PUQE-24 and CORECTS are the first validated scales used to assess the
severity of NVP and hemorrhoids. Proctofoam-HC® is safe and effective for use in
pregnancy.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OTU.1807/30581 |
| Date | 07 December 2011 |
| Creators | Ebrahimi, Neda |
| Contributors | Koren, Gideon |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | en_ca |
| Detected Language | English |
| Type | Thesis |
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