Pre-filled syringes: Examination of the needs for ready-to-administer parenteral drugs at Uppsala University hospital Background: Many parenteral drugs delivered to hospital wards are not ready-to-administer drugs. These drugs are delivered as concentrates or lyophilizates (dry powders) and need preparation by responsible healthcare professionals/nurses before they can be administered. Today, however, there is a shortage of nurses that forces the hospital management to find new ways to free nursing time and open more hospital beds. Aim: The purpose of this study was to examine the consumption of parenteral drugs at the Uppsala University Hospital that could potentially be provided by the extemporaneous manufacturing unit, CBE, as prefilled syringes. Methods: Quantitative data from the Concise Database hosted by the Swedish eHealth Agency was used to derive data on parenteral medications used in Region Uppsala year 2021. Information regarding common drug’s dilutions and shelf life was obtained from the information systems/databases MedMark, MetaVison, and Micromedex. In addition to the collected data, a small sub-study with two nurses was conducted regarding their thoughts on parenteral drug preparation and pre-filled syringes. Results: Quantitative data showed the top 40 most used non-ready to administer drugs for Region Uppsala, year 2021.The most common drugs that need precreation is antibiotics. According to drug stability and shelf-life data, longer shelf life could be obtained using extemporaneous compounding. This cross-sectional study also indicate freed nursing time between 6-11 full-time nursing estimates. Based on the unstructured interviews, positive attitudes are seen towards the provision of parenteral drugs in pre-filled syringes. Conclusion: It can be concluded that ready-to-administer drugs for parenteral use could possibly be provided by CBE, using extemporaneous compounding. This can thereby increase the safety and quality of parenteral drugs used in the clinical environment, and potentially free nursing time.
| Identifer | oai:union.ndltd.org:UPSALLA1/oai:DiVA.org:uu-480853 |
| Date | January 2022 |
| Creators | Alyass, Mina |
| Publisher | Uppsala universitet, Institutionen för farmaci |
| Source Sets | DiVA Archive at Upsalla University |
| Language | Swedish |
| Detected Language | English |
| Type | Student thesis, info:eu-repo/semantics/bachelorThesis, text |
| Format | application/pdf |
| Rights | info:eu-repo/semantics/openAccess |
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