Background: Temporary mechanical circulatory support device without sternotomy has been highly advocated for severe cardiogenic shock patient but little is known when coupled with amniotic stem cell therapy. Case presentation: This case reports the first dual therapy of temporary left ventricular extracorporeal device CentriMag with distal banding technique and human amniotic stem cell injection for treating a severe refractory cardiogenic shock of an 68-year-old female patient. A minimally-invasive off-pump LVAD was established by draining from the left ventricle and returning to the right axillary artery with distal arterial banding to prevent right upper extremity hyperperfusion. Amniotic stem cells were injected intramyocardially at the left ventricular apex, lateral wall, inferior wall, and right subclavian vein. Conclusion: The concomitant use of the temporary minimally-invasive off-pump CentriMag placement and stem cell therapy not only provided an alternative to cardiopulmonary bypass and full-median sternotomy procedures but may have also synergistically enhanced myocardial reperfusion and regeneration.
| Identifer | oai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/625812 |
| Date | 07 September 2017 |
| Creators | Kazui, Toshinobu, Tran, Phat L., Pilikian, Tia R., Marsh, Katie M., Runyan, Raymond, Konhilas, John, Smith, Richard, Khalpey, Zain I. |
| Contributors | Univ Arizona, Dept Surg, Div Cardiothorac Surg, Univ Arizona, Coll Med, Univ Arizona, Dept Physiol Sci, Univ Arizona, Dept Biomed Engn |
| Publisher | BIOMED CENTRAL LTD |
| Source Sets | University of Arizona |
| Language | English |
| Detected Language | English |
| Type | Article |
| Rights | © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License. |
| Relation | http://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-017-0648-7 |
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